Brain Tumor Research Papers

Brain Tumor Research Papers-38
Forrest General became the first hospital in Mississippi to use Gleolan™ (aminolevulinic acid HCl) for enhanced visualization of high-grade gliomas (including glioblastomas), or tumors occurring in the glial cells of the brain.This solution causes tumor cells to glow red under blue light allowing the neurosurgeon to remove as much of the tumor as possible without affecting healthy brain cells.

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A new drug, known as IP1867B, could be used for future treatments of brain tumors.

The research team showed that IP1867B worked with existing cancer treatments boosting their effectiveness and, in some cases, restored sensitivity to some treatments.

The work also has implications for how medulloblastoma is classified, which may eventually shape clinical care.

In immunotherapy for cancer, the buzziest area of research is combinations: one checkpoint drug with another, say, or a checkpoint drug with chemotherapy.

Pharmacy students developed the oral compound RK15.

They said the drug mainly targets the aggressive brain cancer glioblastoma and is very reactive to killing the harmful cells A new study gives insight into how immunotherapies, treatments that help the body's immune system fight cancer, might one day be delivered directly to the brain in order to treat brain tumors.An international team led by researchers has discovered the energy production mechanism of cancerous cells that drives the growth of the nucleolus and causes tumors to rapidly multiply.The findings could lead to the development of new cancer treatments that would stop tumor growth by cutting the energy supply to the nucleolus.Researchers led by Texas A&M University’s College of Veterinary Medicine & Biomedical Sciences have identified a new pathway they believe may help suppress the development of glioblastoma tumors.The pathway in question involves the AH receptor, which controls the expression of a diverse group of genes.The Ivy Brain Tumor Center at the Barrow Neurological Institute, has released the results of its recent Phase 0 clinical trial of the breast cancer drug ribociclib (Kisqali®) for the treatment of recurrent glioblastoma.The agent, recently approved by the FDA for advanced breast cancer, is part of a newly-discovered class of targeted therapy that undermines cancer cell division and could form the backbone of a new drug cocktail for patients with malignant brain tumors like glioblastoma. Jude Children's Research Hospital and Massachusetts General Hospital, alongside others, have revealed the cells of origin for specific subtypes of medulloblastoma, the most common malignant pediatric brain tumor.Your access to the NCBI website at gov has been temporarily blocked due to a possible misuse/abuse situation involving your site.This is not an indication of a security issue such as a virus or attack.A new therapy for treating glioma, an aggressive brain tumor, was shown to be safe in patients and cleared other important hurdles, according to a phase 1 trial recently published in Science Translational Medicine.The therapy induces production of a cancer-fighting cytokine in the brain, which could be less toxic and more effective than delivering the cytokine itself intravenously, In their initial report, the researchers focused on diffuse intrinsic pontine gliomas, or DIPG, an inoperable brainstem tumor found in children.


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